Allegra non sedating antihistamines
Allegra non sedating antihistamines - anna svetlaya dating
systemic, topical or inhaled drugs that antagonize histamine and control allergies, e.g.hayfever (seasonal rhinitis), drug allergies, urticaria (induced by insect bites); injected antihistamine (chlorphenamine) is used as an adjunct to adrenaline in the treatment of anaphylaxis and angioedema; modern antihistamines (e.g.
When used with promethazine (Phenergan) this may cause reduced blood pressure and involuntary movements.
The second generation antihistamines have no central action, and are used only for treatment of allergic reactions. Cetirizine (Zyrtec) is a piperazine derivative, and has a slight sedative effect.
Loratidine (Claritin) and fexofenadine (Allegra) are members of the piperadine class and are essentially non-sedating.
See page 51) are prevalent worldwide, especially in industrialized countries.
Pharmacologic treatment of these disorders continues to improve in efficacy and safety.
Central nervous system reactions include drowsiness, sedation, dizziness, faintness, disturbed coordination, lassitude, confusion, restlessness, excitation, tremor, seizures, headache, insomnia, euphoria, blurred vision, hallucinations, disorientation, disturbing dreams/nightmares, schizophrenic-like reactions, weakness, vertigo, hysteria, nerve pain, and convulsions. Not all apply to every drug, and some reactions may not be drug related.
Some of the other adverse effects are chest tightness; wheezing; nasal stuffiness; dry mouth, nose and throat; sore throat; respiratory depression; sneezing; and a burning sensation in the nose.
If an antihistamine fails to provide adequate relief, switch to a drug from a different chemical class.
Individual drugs may be effective in no more than 40% of patients, and provide 50% relief of allergic symptoms. A large number of additional reactions have been reported.
acrivastine, cetirizine) tend not to cause sedation, such as loratadine (Claritin), which recently moved from prescription-only to OTC status, desloratadine (Clarinex), cetirizine (Zyrtec) and fexofenadine (Allegra), were developed to minimize the adverse events observed with the earlier agents while maintaining efficacy.
Original publication date – February 2010 (revised March 2012) Download PDF version Allergic rhinitis, allergic conjunctivitis, atopic dermatitis, urticaria, anaphylaxis and asthma (not included here; reviewed in 2012; .
The second-generation antihistamines bind only to peripheral HThe first-generation antihistamines may be divided into several chemical classes.